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[Cardiac failure in endocrine diseases]

K Hashizume1

  • 1Department of Geriatrics, Endocrinology and Metabolism, Shinshu University School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|May 1, 1993
PubMed
Summary

Endocrine diseases like acromegaly and hypothyroidism can cause severe cardiac failure. Understanding these connections is crucial for diagnosing and managing heart conditions linked to hormonal imbalances.

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Area of Science:

  • Endocrinology
  • Cardiology
  • Internal Medicine

Context:

  • Cardiac failure is a common symptom in several endocrine diseases.
  • Specific endocrine disorders manifest distinct forms of cardiac dysfunction.
  • Hormonal imbalances significantly impact cardiovascular health.

Purpose:

  • To review the relationship between various endocrine diseases and cardiac failure.
  • To highlight the specific cardiac manifestations associated with each endocrine condition.
  • To emphasize the importance of considering endocrine disorders in patients with heart failure.

Summary:

  • Acromegaly leads to left-sided cardiac failure due to specific cardiomyopathy.
  • Hypoparathyroidism causes cardiac failure linked to hypocalcemia and low parathyroid hormone.
  • Hypothyroidism (myxedemal coma) results in severe cardiac failure with multi-organ dysfunction.
  • Thyroid crisis (storm) induces cardiac failure from reduced cardiac output and dehydration.
  • Pheochromocytoma can precipitate cardiac failure (shock) post-adrenal tumor removal due to circulatory volume reduction.
  • Malignant carcinoid syndrome is associated with right-sided ventricular failure, potentially mediated by biogenic amines.

Impact:

  • Provides a comprehensive overview of endocrine-related cardiac failure.
  • Aids clinicians in recognizing and diagnosing cardiac issues stemming from endocrine disorders.
  • Underscores the need for integrated diagnosis and management of endocrine and cardiac conditions.

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