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Related Experiment Videos

Bronchial carcinoid tumors

D G Davila1, W F Dunn, H D Tazelaar

  • 1Division of Thoracic Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.

Mayo Clinic Proceedings
|August 1, 1993
PubMed
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Bronchial carcinoid tumors are rare neuroendocrine lung neoplasms. Surgical resection offers the best prognosis, which depends on tumor grade and stage.

Area of Science:

  • Pulmonology
  • Oncology
  • Pathology

Background:

  • Bronchial carcinoid tumors, previously termed bronchial adenomas, are uncommon neuroendocrine pulmonary neoplasms.
  • These tumors originate from neuroendocrine cells and can secrete various chemical substances.
  • They are classified as typical or atypical, with atypical carcinoids exhibiting higher malignant potential.

Purpose of the Study:

  • To provide a comprehensive overview of bronchial carcinoid tumors.
  • To discuss their classification, clinical presentation, diagnosis, and management.
  • To highlight the relationship between prognosis and tumor characteristics.

Main Methods:

  • Review of existing literature on bronchial carcinoid tumors.
  • Analysis of tumor classification, location, and associated syndromes.

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  • Discussion of diagnostic imaging and treatment modalities.

    • Main Results:

    • Approximately 75% of bronchial carcinoids are found in lobar bronchi, 10% in main-stem bronchi, and 15% peripherally.
    • Well-differentiated (typical) carcinoids comprise nearly 90% of cases.
    • Carcinoid syndrome is rare, but Cushing's syndrome can occur due to ectopic hormone production.
    • Conventional chest roentgenograms detect over 75% of these tumors; CT aids in identifying occult lesions.

    Conclusions:

    • Bronchial carcinoid tumors are neuroendocrine neoplasms requiring accurate diagnosis and classification.
    • Pulmonary resection is the primary treatment, with prognosis tied to pathologic grade and stage.
    • Understanding tumor characteristics is crucial for effective patient management and outcomes.