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[Dysphagia in multiple system atrophy--radiological and manometric study]

K Kurihara¹, K Kita, K Hirayama

¹Department of Neurology, School of Medicine, Chiba University.

Rinsho Shinkeigaku = Clinical Neurology

|March 1, 1993

Summary

Multiple system atrophy (MSA) patients exhibit dysphagia, characterized by swallowing and passage disturbances. Manometric and radiological studies revealed upper esophageal sphincter dysfunction and esophageal motility issues in these patients.

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Area of Science:

Neurology
Gastroenterology
Speech-Language Pathology

Background:

Multiple system atrophy (MSA) is a neurodegenerative disorder affecting various involuntary functions.
Dysphagia is a common and often debilitating symptom in MSA patients, impacting quality of life.

Purpose of the Study:

To investigate the characteristics of dysphagia in patients with multiple system atrophy (MSA).
To differentiate between swallowing and passage disturbances in MSA-related dysphagia.
To correlate clinical, radiological, and manometric findings with dysphagia types in MSA.

Main Methods:

Clinical assessment of dysphagia, including history taking to distinguish swallowing and passage disturbances.
Radiological examination using X-rays with contrast medium (Dionosil) to visualize swallowing phases.

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Esophageal manometry to measure intraluminal resting pressure and esophageal contraction pressure.

Main Results:

13 patients reported swallowing disturbances, and 4 reported passage disturbances.
Radiological findings included lingual movement disorders (6 patients), piriformis sinus pooling (11 patients), and lower esophageal dilatation (14 patients).
Manometric studies indicated low intraluminal resting pressure of the upper esophageal sphincter in 12 patients.

Conclusions:

Dysphagia in MSA presents with both swallowing and passage difficulties.
Radiological and manometric findings highlight oropharyngeal and esophageal motility impairments in MSA patients.
Upper esophageal sphincter dysfunction is a significant finding in MSA-related dysphagia.