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[An applied study on the method of multi-factorial quantitative-risk assessment (MFQRA) for mass screening of
1Department of Epidemiology, Zhejiang Medical University, Hangzhou.
Abstract:
This paper reported an actual effectiveness evaluation for MFQRA, as a primary screening procedure, applied in a mass screening for colorectal cancer since 1989 to 1990 among a general population with the age of 30 and above in Jia-shan county where is a high incidence area of colorectal cancer in this nation. Results of this paper demonstrated that (1) attributable degree (AD) can identify subpopulations or subgroups with different incidence risks from a general population, and provide evidence for decision-making of advanced screening procedures and even for prevention of colorectal cancer; (2) Sensitivity of MFQRA was much higher, compared to conventional fecal occult blood test (FOBT) and symptomatic screening methods (65.89% vs 34%-50%); (3) Multiple tests with FOBT by reverse passive hemagglutination (RPHA) were effective and practical method for mass screening of colorectal cancer.
