[131I-ortho-iodohippurate renography in the staging of malignant lymphoma]

Malignant lymphoma is a systemic disease with many organs involved. According to autopsy reports, the frequency of kidney involvement was 60% and with no symptoms, signs and serum biochemical abnormalities in most of the patients. 131I-sodium orthoiodohippurate (131I-OIH) renography examination was performed in 33 malignant lymphoma cases. It was abnormal in 20 cases (60.6%). Major abnormalities were tb, C1/2 extension and decrease in RI. "Obstructive type" renography could be found in a number of the patients. An obstructive type renography seen in one patient showed improvement after chemotherapy, but autopsy revealed that both kidneys were involved. It suggested that the renography abnormality was related to tumor infiltration. Among the 33 cases, there were 13 abnormal renographies in I-III stage patients. Examination was performed in 8 cases both before and after chemotherapy, and their renographies were improved after chemotherapy (remission rate 100%). Therefore, we believe that renography examination is advantageous to make accurate staging of malignant lymphoma.