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Sequence of the Proteus mirabilis urease accessory gene ureG
B Sriwanthana1, M D Island, H L Mobley
1Department of Medicine, University of Maryland School of Medicine, Baltimore, 21201.
Gene
|July 15, 1993
Abstract:
We report the sequence of ureG, an accessory gene that is a part of the ure gene cluster of uropathogenic Proteus mirabilis and required for full enzymatic activity of urease. The 615-bp open reading frame predicts a M(r) 22,374 polypeptide, which contains a consensus amino acid (aa) sequence for ATP-binding. The polypeptide shares sequence homology with UreG of Escherichia coli (93% of identical aa), Klebsiella aerogenes (59%) and Helicobacter pylori (59%).