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Published on: November 30, 2010
The increasing incidence of infantile hypertrophic pyloric stenosis
J M O'Donoghue1, K D Connolly, M M Gallagher
1Department of Surgery, Portiuncula Hospital, Galway.
Insights
The incidence of infantile hypertrophic pyloric stenosis (IHPS) significantly increased in West Ireland from 1981 to 1990. This rise in IHPS cases occurred despite stable birth rates, with causes remaining unclear.
Area of Science:
- Pediatric Gastroenterology
- Epidemiology
- Public Health
Background:
- Infantile hypertrophic pyloric stenosis (IHPS) is a condition affecting infants.
- Previous studies indicated a potential rise in IHPS incidence.
Purpose of the Study:
- To investigate the incidence trends of IHPS in a defined population.
- To analyze IHPS rates over a ten-year period in West Ireland.
Main Methods:
- Retrospective analysis of IHPS cases.
- Utilized live birth data from West Ireland (1981-1990).
- Statistical analysis to determine incidence changes and correlations.
Main Results:
- A significant increase in IHPS incidence was observed, from 0.87/1000 live births in 1981 to 5.10/1000 in 1990.
- The incidence peaked in 1989 at 6.8/1000 live births.
- No correlation found between IHPS incidence and feeding habits, birth rank, family history, or gender.
Conclusions:
- The incidence of IHPS has significantly increased in West Ireland between 1981 and 1990.
- The underlying reasons for this observed increase in IHPS are not identified by this study.
- Further research is needed to elucidate the causes of rising IHPS rates.
Abstract:
Several reports have suggested that there is an increasing incidence of infantile hypertrophic pyloric stenosis (IHPS). We examined the incidence of IHPS in a stable population in the West of Ireland over a ten year period (1981-1990). During the 10 years of the study the number of live births per year did not alter significantly. The incidence of IHPS increased significantly from 0.87/1000 live births in 1981 to 5.10/1000 in 1990 (p < 0.001, Student's test), peaking in 1989 at 6.8/1000. There was no statistical correlation between the increasing incidence and feeding habits, birth rank, family history or gender distribution. The reason(s) for this increase remain unclear.
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