[Endovascular therapy with laser light in the combined treatment of acute pancreatitis]

Studies conducted in experiments (132 animals) and in the clinic (109 patients) revealed a close relationship between the severity of pancreatogenous endotoxicosis and red cell membrane hyperlipoperoxidation and spontaneous red cell hemolysis, which allows three degrees of blood red cell lipoperoxidation to be distinguished in the period of acute endotoxemia: mild, moderate, and severe. Inclusion of blood laser irradiation into the management of acute pancreatogenous toxemia in moderate and severe degrees of blood red cell hyperlipoperoxidation reduces authentically the peroxide damage of the red cell membranes and the marked character of hemic hypoxia. The best effect was produced with the use of LG-75-1 laser beam in an elaborated regimen in severe red cell lipoperoxidation. The content of secondary lipoperoxidation products reduces in this case by 28.5% on the average in significant correlation with normalization of some clinical and laboratory parameters.