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[Weber syndrome caused by Listeria abscess]
L Milandre1, P Pestre, D Figarella-Branger
1Service de Neurologie, CHU Timone.
Revue Neurologique
|January 1, 1993
Summary
A diabetic man developed Listeria monocytogenes meningitis, presenting with Weber's syndrome and neurological symptoms. Despite treatment, he died from heart failure, with autopsy revealing mesencephalic abscesses.
Area of Science:
- Neurology
- Infectious Diseases
- Internal Medicine
Background:
- Listeria monocytogenes is a significant cause of bacterial meningitis, particularly in immunocompromised individuals.
- Weber's syndrome, a rare brainstem stroke, can present with diverse neurological deficits.
- Meningitic syndrome involves inflammation of the meninges, often indicated by pleocytosis and elevated protein in cerebrospinal fluid.
Observation:
- A 63-year-old diabetic patient presented with symptoms of left Weber's syndrome and meningitis.
- Cerebrospinal fluid analysis revealed lymphocytic pleocytosis and elevated protein, with normal glucose and negative cultures.
- Blood cultures confirmed Listeria monocytogenes infection.
Findings:
- The patient received ampicillin for Listeria monocytogenes meningitis.
- Neurological symptoms showed partial improvement during treatment.
- The patient ultimately succumbed to heart failure.
Implications:
- This case highlights the potential for Listeria monocytogenes to cause severe neurological complications, including brain abscesses.
- Early diagnosis and appropriate antibiotic therapy are crucial for managing Listeria meningitis.
- The case underscores the importance of considering infectious etiologies in patients with complex neurological presentations, even in the presence of other comorbidities.