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Progressive cerebral calcifications, epilepsy, and celiac disease
A Fois1, P Balestri, M Vascotto
1Department of Pediatrics, University of Siena, Italy.
Brain & Development
|January 1, 1993
Summary
A 9-year-old boy with progressive brain calcifications and epilepsy was diagnosed with celiac disease (CD). This case highlights the potential link between celiac disease and neurological conditions like epilepsy.
Area of Science:
- Neurology
- Gastroenterology
- Pediatrics
Background:
- Epilepsy and progressive cerebral calcifications can present with complex etiologies.
- Celiac disease (CD) is an autoimmune disorder typically affecting the small intestine.
Observation:
- A 9-year-old boy presented with drug-resistant epilepsy and progressive white matter involvement with cerebral calcifications.
- Extensive neurological investigations were performed to determine the underlying cause.
Findings:
- The final diagnosis for the patient's neurological symptoms was celiac disease (CD).
- This suggests a potential association between CD and the development of epileptogenic lesions in the brain.
Implications:
- This case underscores the importance of considering celiac disease in pediatric patients with unexplained neurological disorders.
- Further research is warranted to elucidate the mechanisms linking celiac disease to neurological manifestations and epilepsy.