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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Articles linked to this work by shared authors, journal, and citation graph.

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Skin test reactions to Mycobacterium tuberculosis purified protein derivative and Mycobacterium avium sensitin among health care workers and medical students in the United States.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2002
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T cells enhance production of IL-18 by monocytes in response to an intracellular pathogen.

Journal of immunology (Baltimore, Md. : 1950)·2001
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Contribution of CD8(+) T cells to gamma interferon production in human tuberculosis.

Infection and immunity·2001
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Diagnosing latent tuberculosis infection: the 100-year upgrade.

American journal of respiratory and critical care medicine·2001
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Induction of direct antimicrobial activity through mammalian toll-like receptors.

Science (New York, N.Y.)·2001
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Cytokine profiles in immunocompetent persons infected with Mycobacterium avium complex.

The Journal of infectious diseases·2001

Related Experiment Video

Updated: Jun 14, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Tuberculosis in the 1990s

P F Barnes1, S A Barrows

  • 1University of Southern California School of Medicine, Los Angeles.

Annals of Internal Medicine
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

Recent tuberculosis (TB) increases affect minority groups and those with HIV. New DNA techniques aid diagnosis and transmission tracking, while ensuring treatment compliance is crucial for controlling drug-resistant TB.

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Last Updated: Jun 14, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

Area of Science:

  • Infectious Diseases
  • Public Health
  • Microbiology

Background:

  • Tuberculosis (TB) morbidity has increased in the U.S., particularly among specific demographics.
  • Drug-resistant TB poses a significant challenge to effective treatment.

Purpose of the Study:

  • To review recent advancements in tuberculosis diagnosis, treatment, and prevention.
  • To highlight current strategies for managing TB.

Main Methods:

  • Literature search of MEDLINE and relevant bibliographies since 1987.
  • Selection of 101 key references for practicing internists.

Main Results:

  • Polymerase chain reaction (PCR) and DNA fingerprinting offer rapid TB diagnosis and transmission pattern analysis.
  • Effective treatment regimens for drug-susceptible TB achieve over 95% cure rates.
  • Non-compliance with medication leads to rising rates of multidrug-resistant TB.

Conclusions:

  • Improved implementation of diagnostic, treatment, and preventive measures is essential for TB control.
  • Ensuring patient compliance with tuberculosis therapy is a critical focus for future efforts.