Bilateral transient keratoendotheliitis associated with systemic lupus erythematosus

Numerous ocular manifestations have been attributed to systemic lupus erythematosus (SLE) and other collagen vascular diseases. Only one report has been published discussing an entity of transient corneal edema associated with SLE, which was attributed to keratoendotheliitis. We report the case of a 45-year-old woman with long-standing SLE and severe central nervous system involvement in whom bilateral transient corneal edema developed that was responsive to topical and systemic corticosteroid treatment over a four-week period. We believe this case may also represent an inflammatory keratoendotheliitis associated with SLE.