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Bilateral transient keratoendotheliitis associated with systemic lupus erythematosus
1Dean A. McGee Eye Institute Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City 73104.
Summary
Systemic lupus erythematosus (SLE) can cause eye problems. This case highlights transient corneal edema in an SLE patient, potentially due to inflammatory keratoendotheliitis, which responded to corticosteroids.
Area of Science:
- Ophthalmology
- Rheumatology
- Systemic Lupus Erythematosus (SLE)
Background:
- Ocular manifestations are common in collagen vascular diseases like SLE.
- Previous literature documented only one case of transient corneal edema linked to SLE, attributed to keratoendotheliitis.
Observation:
- A 45-year-old woman with a history of severe central nervous system involvement due to SLE presented with bilateral transient corneal edema.
- The corneal edema resolved over a four-week period.
Findings:
- The patient's corneal edema responded effectively to both topical and systemic corticosteroid therapy.
- This presentation is consistent with inflammatory keratoendotheliitis associated with SLE.
Implications:
- This case expands the understanding of ocular manifestations in SLE.
- It suggests that inflammatory keratoendotheliitis is a potential cause of transient corneal edema in SLE patients.
- Prompt corticosteroid treatment may be beneficial for managing this specific ocular complication of SLE.