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Published on: September 9, 2012
Successful childbirth by a patient with congenital factor XI deficiency and an acquired inhibitor
S S Ginsberg1, L P Clyne, P McPhedran
1Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510.
British Journal of Haematology
|May 1, 1993
Abstract:
Acquired inhibitors in factor XI deficiency (FXI) are rare. The presence of an inhibitor during pregnancy poses a potential haemorrhagic risk to the fetus. We report an uncomplicated pregnancy and successful childbirth by a woman with congenital FXI deficiency and an acquired inhibitor, and discuss the persistence of residual FXI activity in the presence of an inhibitor.

