Related Experiment Video
Updated: Jul 23, 2026

15:43
Experimental Generation of Carcinoma-Associated Fibroblasts (CAFs) from Human Mammary Fibroblasts
Published on: October 25, 2011
Formation of solid human mammary carcinoma in vitro
Journal of the National Cancer Institute
|February 1, 1977
Abstract:
An established line of human breast carcinoma, MCF-7, when cultured within the artificial capillary system, formed solid masses of tissue. Acinar and ductular patterns developed, having the ultrastructural appearance of breast tissue that responds to exogenous hormones.

