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Parity, lactation and hip fracture

S Hoffman1, J A Grisso, J L Kelsey

  • 1Division of Epidemiology, Columbia University School of Public Health, New York, NY 10032.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|July 1, 1993
PubMed
Summary

Having a live birth may reduce the risk of hip fracture in women. Each birth was associated with a slight, though not statistically significant, decrease in hip fracture odds.

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Area of Science:

  • Epidemiology
  • Orthopedics
  • Reproductive Health

Background:

  • Hip fractures represent a significant public health concern, particularly in aging populations.
  • Parity and lactation are key reproductive factors that may influence bone health and fracture risk.

Purpose of the Study:

  • To investigate the association between parity (number of live births) and lactation and the incidence of hip fracture in white women.
  • To determine if reproductive history modifies hip fracture risk in women aged 45 and over.

Main Methods:

  • A case-control study design was employed, involving 174 women with hip fractures (cases) and 174 age- and hospital-matched controls.
  • Data were collected from admissions to 30 hospitals in New York and Philadelphia between 1987 and 1989.
  • Statistical analyses controlled for age, hospital of recruitment, and body mass index.

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Main Results:

  • Women who had ever had a live birth had reduced odds of hip fracture (OR = 0.65).
  • Each live birth was associated with a 9% average reduction in hip fracture odds (OR = 0.92), though this trend was not statistically significant.
  • Lactation duration was not significantly associated with hip fracture risk after adjusting for the number of births.

Conclusions:

  • Parity, specifically having live births, appears to be associated with a lower risk of hip fracture in women.
  • The findings suggest that reproductive factors play a role in hip fracture etiology, warranting further investigation.
  • Lactation's direct impact on hip fracture risk, independent of birth number, was not supported by this study.