Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Body fluid changes during hypertonic lactated saline solution therapy for burn shock

S Shimazaki, T Yoshioka, N Tanaka

    The Journal of Trauma
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Abnormal chest shadow on CT in immunosuppressed patients].

    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica·1992
    Same author

    Bowel preparation for the total colonoscopy by 2,000 ml of balanced lavage solution (Golytely) and sennoside.

    Gastroenterologia Japonica·1992
    Same author

    [Determination of common esterase D phenotypes by HPLC].

    Journal of UOEH·1992
    Same author

    Acute superior mesenteric artery syndrome following left hemicolectomy: a case report.

    Acta medica Okayama·1992
    Same author

    Proton irradiation for hepatocellular carcinoma.

    Lancet (London, England)·1992
    Same author

    [Prediction of ovulation by urinary LH surge].

    Nihon Naibunpi Gakkai zasshi·1992

    Hypertonic Lactate Saline (HLS) therapy in burn patients required less fluid volume than isotonic therapy. HLS effectively maintained extracellular fluid volume during shock and postresuscitation.

    Area of Science:

    • Burn patient resuscitation
    • Fluid management in critical care
    • Hypertonic saline therapy

    Background:

    • Burn injuries cause significant fluid shifts and edema.
    • Traditional isotonic fluid resuscitation can lead to fluid overload.
    • Optimizing fluid therapy is crucial for burn patient outcomes.

    Purpose of the Study:

    • To compare body fluid changes in burn patients treated with Hypertonic Lactate Saline (HLS) versus isotonic therapy.
    • To evaluate the efficacy of HLS in maintaining extracellular fluid volume.
    • To discuss potential clinical challenges associated with HLS.

    Main Methods:

    • Retrospective comparison of 12 burn patients receiving HLS and 26 receiving isotonic therapy.
    • Analysis of total infusion volume and sodium load within the first 48 hours postburn.

    Related Experiment Videos

  • Assessment of functional extracellular fluid volume (f-ECFV) changes.

    • Main Results:

    • HLS group received 50-67% less fluid volume than the isotonic group, with similar sodium loads.
    • HLS therapy preserved adequate f-ECFV during the shock phase.
    • HLS therapy prevented excessive f-ECFV expansion in the postresuscitative phase.

    Conclusions:

    • Hypertonic Lactate Saline therapy may be a more efficient fluid resuscitation strategy for burn patients.
    • HLS demonstrates potential in managing extracellular fluid volume dynamics postburn.
    • Further investigation into managing hypernatremia and intracellular fluid shifts with HLS is warranted.