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Optic neuritis associated with familial Mediterranean fever
A Lossos1, S Eliashiv, E Ben-Chetrit
1Department of Neurology, Hadassah Hebrew University Hospital, Jerusalem, Israel.
Journal of Clinical Neuro-Ophthalmology
|June 1, 1993
Summary
Familial Mediterranean fever (FMF), an inherited inflammatory disorder, is rarely associated with neuro-ophthalmologic conditions. This report details a novel link between FMF and optic neuritis in two patients.
Area of Science:
- Neurology
- Ophthalmology
- Genetics
Background:
- Familial Mediterranean fever (FMF) is a rare inherited autoinflammatory disease.
- Characterized by recurrent fever and polyserositis, its etiology remains largely unknown.
- Neuro-ophthalmologic manifestations of FMF are exceptionally uncommon.
Observation:
- Two patients with diagnosed Familial Mediterranean fever presented with optic neuritis.
- Optic neuritis, inflammation of the optic nerve, is not a typical FMF symptom.
- This observation highlights a potential, previously undocumented association.
Findings:
- The study identifies a potential link between Familial Mediterranean fever and optic neuritis.
- This association was observed in two distinct patient cases.
- Further research is warranted to explore this connection.
Implications:
- This finding may expand the known clinical spectrum of Familial Mediterranean fever.
- It suggests that neuro-ophthalmologic evaluation could be considered in FMF patients presenting with relevant symptoms.
- Understanding this association could improve diagnostic and management strategies for FMF.