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Related Experiment Videos

Topical anesthesia during circumcision in newborn infants

F Benini1, C C Johnston, D Faucher

  • 1Division of Nursing Research, McGill University-Montreal Children's Hospital, Quebec, Canada.

JAMA
|August 18, 1993
PubMed
Summary

Topical anesthetic cream, eutectic mixture of local anesthetics (EMLA), effectively reduces pain during neonatal circumcision. This study shows EMLA significantly alleviates pain responses in newborns undergoing the procedure.

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Area of Science:

  • Neonatal care
  • Pain management
  • Pediatric surgery

Background:

  • Neonatal circumcision is a common procedure associated with pain.
  • Effective pain management is crucial for infant well-being during procedures.

Purpose of the Study:

  • To evaluate the efficacy of eutectic mixture of local anesthetics (EMLA) cream in reducing pain during neonatal circumcision.

Main Methods:

  • A randomized, controlled trial was conducted in a university hospital's newborn nursery.
  • Twenty-seven full-term male neonates (1-3 days old) were included.
  • Pain was assessed using heart rate, oxygen saturation, facial activity, and crying.

Main Results:

  • Circumcision induced significant pain responses, including increased heart rate, decreased oxygen saturation, and more facial activity.

Related Experiment Videos

  • EMLA significantly reduced heart rate, improved oxygen saturation, and decreased facial activity and crying compared to placebo.
  • No differences in spectral crying parameters were observed between groups.

    • Conclusions:

    • The circumcision procedure elicits measurable pain responses in neonates.
    • EMLA demonstrates efficacy in diminishing these pain responses.
    • EMLA is a potentially valuable agent for managing pain associated with neonatal circumcision.