Related Experiment Video
Updated: Aug 16, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[Perinatology. Fetal origin of diseases in adults]
1U.Z. Gasthuisberg Verloskunde-Gynaecologie, Leuven.
Insights
Perinatal medicine focuses on normal fetal development. Issues during fetal growth, influenced by the intrauterine environment, can lead to long-term health problems in infancy and adulthood, as seen in diabetes and pregnancy complications.
Area of Science:
- Perinatal Medicine
- Fetal Development
- Developmental Origins of Health and Disease
Background:
- Perinatal medicine prioritizes understanding normal fetal growth and development.
- The intrauterine environment significantly impacts fetal development, with implications for later life.
- Disruptions in fetal development can stem from an abnormal intrauterine milieu.
Purpose of the Study:
- To highlight the critical importance of perinatal care in monitoring fetal development.
- To underscore the long-term consequences of abnormal fetal development originating in utero.
- To emphasize the link between intrauterine conditions and subsequent infant and adult health.
Main Methods:
- Review of current understanding in perinatal medicine.
- Analysis of the impact of intrauterine conditions on fetal development.
- Examination of evidence linking fetal development disorders to later health outcomes.
Main Results:
- Disorders in fetal development due to an abnormal intrauterine environment are linked to problems in infancy and adulthood.
- Conditions such as diabetes in pregnancy and intrauterine growth retardation exemplify this link.
- Effective perinatal care is crucial for mitigating long-term health issues.
Conclusions:
- Perinatal care plays a vital role in ensuring healthy fetal development.
- An abnormal intrauterine milieu can have lasting adverse effects on health.
- Early identification and management of fetal development issues are essential for long-term well-being.
Abstract:
Perinatal medicine is mostly interested in the normal development of the growing fetus. Perinatal care is becoming even more important, since a disorder in fetal development, due to an abnormal intrauterine milieu, results in problems during infancy and adult age. There is clear evidence that this is the case in diabetes and pregnancy and in intrauterine growth retardation.
More Related Videos
08:50A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
05:44Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1
Published on: May 17, 2024
Related Concept Videos
Meiosis vs. Mitosis
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Smooth Endoplasmic Reticulum
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
Teratogenicity
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Development of the Oral Microbiota
Diabetic Retinopathy