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Familial lupoid thrombocytopenia
K Shimizu1, I Katsuta, T Uchikawa
1Department of Medicine, Fujita Health University School of Medicine, Nagoya, Japan.
Familial lupoid thrombocytopenia affecting three subjects in three generations is reported. All subjects had antinuclear antibodies with or without antibodies to single-stranded DNA, an increase in platelet-associated IgG, and a family member with an autoimmune disease. These findings implicate a genetic contribution. All subjects shared a common HLA haplotype.
Familial lupoid thrombocytopenia affecting three subjects in three generations is reported. All subjects had antinuclear antibodies with or without antibodies to single-stranded DNA, an increase in platelet-associated IgG, and a family member with an autoimmune disease. These findings implicate a genetic contribution. All subjects shared a common HLA haplotype.