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Intracavernous sodium nitroprusside: inappropriate impotence treatment
1Department of Urology, University of California Medical School, San Francisco 94143-0738.
The Journal of Urology
|September 1, 1993
Abstract:
On the basis of reports describing nitric oxide as a form of endothelium-derived relaxing factor and on our own experience with intracavernous use of nitric oxide-releasing substances in animal models, we undertook an approved human study of intracavernous sodium nitroprusside as a treatment for impotence. We report our early experience in which severe hypotension and only mild tumescence in our first 3 patients caused us to discontinue the trial.