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[Changes in hemocoagulation in children with cranio-cerebral trauma]
D Pospísil1, E Kohoutová, M Klimovic
1ARO Fakultní dĕtské nemocnice J. G. Mendela, Brno-Cerná Pole.
Insights
This study monitored coagulation changes in children with head injuries, identifying "latent consumption coagulopathy" where lab results don't match clinical signs. Disseminated coagulopathy is also discussed as a complication of craniocerebral injuries.
Area of Science:
- Pediatric critical care medicine
- Hematology
- Neurology
Context:
- Craniocerebral injuries in children present complex challenges.
- Monitoring the hemostasis system is crucial for managing these patients.
- The study was conducted during the first year of a dedicated pediatric acute respiratory observation ward.
Purpose:
- To investigate alterations in the hemostasis system in pediatric patients with craniocerebral injuries.
- To characterize common coagulopathies observed in this patient population.
- To discuss the pathophysiology, diagnosis, and treatment of these coagulation disorders.
Summary:
- The authors observed changes in the hemostasis system in children hospitalized with craniocerebral injuries.
- A prevalent finding was "latent consumption coagulopathy," characterized by laboratory abnormalities without clear clinical manifestations.
- Disseminated consumption coagulopathy was also noted as a severe complication, often secondary to the primary injury.
Impact:
- Provides insights into the spectrum of coagulopathies following pediatric head trauma.
- Highlights the importance of laboratory monitoring for detecting subclinical coagulation abnormalities.
- Informs clinical management strategies for children with craniocerebral injuries and associated hemostatic disturbances.
Abstract:
The authors monitored in children with craniocerebral injuries hospitalized in their department in the course of the more than one-year existence of the child ARO ward in addition to other vital parameters also changes of the haemocoagulation system. They describe the majority of commonly observed abnormalities as "latent consumption coagulopathy", where laboratory findings are not associated with clinical signs of coagulopathy. On the other end of the spectrum of coagulopathies after head injuries is the unit of disseminated consumption coagulopathy which is generally evaluated as a secondary phenomenon or as an intermediary mechanism of the disease which complicates various pathological conditions incl. craniocerebral injuries. The authors discuss the pathophysiology, diagnostic possibilities and their experience with the treatment of the mentioned disorders.