Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantitative echo contrast concentration measurement by Doppler sonography

K Q Schwarz1, G P Bezante, X Chen

  • 1Department of Medicine, University of Rochester, NY 14642.

Ultrasound in Medicine & Biology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anorexia nervosa and heart disease: a systematic review.

Eating and weight disorders : EWD·2018
Same author

Metabolic syndrome is associated with left ventricular dilatation in primary hypertension.

Journal of human hypertension·2015
Same author

[Selection of candidates for cardiac resynchronisation therapy and prediction of their response.].

La Clinica terapeutica·2010
Same author

Sub-clinical organ damage in hypertension and obesity.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2010
Same author

Hypoadiponectinemia in lipodystrophic HIV individuals: a metabolic marker of subclinical cardiac damage.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2009
Same author

Contrast medium induced nephropathy: new insights into prevention and risk management.

Cardiovascular & hematological agents in medicinal chemistry·2009

Doppler ultrasound intensity can quantify relative echo contrast concentrations in flow systems. However, absolute measurements are unreliable due to the microbubble agents' effervescent nature.

Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Fluid Dynamics

Background:

  • Quantitative echo contrast measurements are crucial for assessing blood flow.
  • Doppler ultrasound is commonly used for flow assessment in vessels and chambers.
  • Existing imaging techniques have limitations in quantifying contrast agents.

Purpose of the Study:

  • To investigate the utility of Doppler ultrasound intensity for quantitative echo contrast concentration measurements.
  • To demonstrate the potential and limitations of using scattered ultrasound intensity.
  • To compare audio Doppler intensity with known echo contrast concentrations in a controlled flow system.

Main Methods:

  • Utilized a controlled in vitro flow system to test Doppler ultrasound.

Related Experiment Videos

  • Compared audio Doppler intensity with various steady-state echo contrast concentrations.
  • Performed 62 paired measurements of audio Doppler intensity and echo contrast concentration.

    • Main Results:

    • A weak positive correlation (r = 0.510, p = 0.001) was observed between absolute echo contrast concentration and audio Doppler intensity.
    • A strong correlation (r = 0.958, p = 0.0001) was found between audio Doppler intensity and relative echo contrast concentration over short periods.
    • The weak correlation for absolute concentration is attributed to the effervescent nature of microbubble agents.

    Conclusions:

    • Doppler ultrasound intensity can quantitatively measure relative echo contrast concentration in in vitro flow systems.
    • Absolute echo contrast concentration measurements using this method are currently unreliable.
    • Further research is needed to overcome limitations associated with microbubble contrast agents.