Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intranasal caffeine and amphetamine causing stroke

G L Lambrecht1, M L Malbrain, S L Chew

  • 1Department of Internal Medicine, AZ Stuivenberg, Antwerpen 6, Belgium.

Acta Neurologica Belgica
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CMV gastritis in the immunocompetent host.

Acta gastro-enterologica Belgica·2015
Same author

Validation study of Nexfin® continuous non-invasive blood pressure monitoring in critically ill adult patients.

Minerva anestesiologica·2014
Same author

A Systematic Review And Individual Patient Data Meta-Analysis On Intraabdominal Hypertension In Critically Ill Patients: The Wake-Up Project World Initiative on Abdominal Hypertension Epidemiology, a Unifying Project (WAKE-Up!).

Minerva anestesiologica·2013
Same author

Awareness and practice of breast self examination among malaysian women with breast cancer.

Asian Pacific journal of cancer prevention : APJCP·2011
Same author

Elasticity, thermal stability and bioactivity of polyhedral oligomeric silsesquioxanes reinforced chitosan-based microfibres.

Journal of materials science. Materials in medicine·2011
Same author

The effect of exogenous glucocorticoids on plasma catecholamines and metanephrines in patients without phaeochromocytomas.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2011
Same journal

A rare case of severe hypertension following unilateral iatrogenic glossopharyngeal nerve injury during tonsillectomy.

Acta neurologica Belgica·2026
Same journal

Synergistic pain relief in cervical radiculopathy: A randomized trial of topical methylcobalamin gel with phonophoresis and Mulligan mobilization.

Acta neurologica Belgica·2026
Same journal

Characterizing cranial tremors in a case of spinocerebellar ataxia type 12: a unique positional tremor.

Acta neurologica Belgica·2026
Same journal

A case of coexistence of spinal intradural capillary hemangioma and craniocervical junction dural arteriovenous fistula.

Acta neurologica Belgica·2026
Same journal

Comment on "Content quality and reliability of youtube exercise videos for parkinson's disease".

Acta neurologica Belgica·2026
Same journal

A novel CHMP2B variant of uncertain significance in a patient with apathy, hyperorality, and mild language impairment.

Acta neurologica Belgica·2026
See all related articles

Nasal amphetamine and caffeine use may cause ischemic stroke in young adults, potentially by inducing transient arterial hypertension. This case highlights a previously unreported association between stimulant nasal use and cerebrovascular events.

Area of Science:

  • Neurology
  • Toxicology
  • Cardiology

Background:

  • Cerebrovascular events, particularly ischemic stroke, can be associated with substance abuse.
  • The use of stimulant drugs, including amphetamines and caffeine, has been linked to cardiovascular complications.

Observation:

  • A case report of a 37-year-old man presenting with ischemic stroke following the nasal administration of amphetamine and caffeine.
  • The patient exhibited transient arterial hypertension, which was hypothesized as the causative mechanism for the stroke.
  • Mitral annular calcification was noted but deemed unlikely to be a significant factor.

Findings:

  • No evidence of a hypercoagulable state (primary or secondary) was found in the patient.
  • The stroke occurred subsequent to the nasal use of amphetamine and caffeine.

Related Experiment Videos

  • Literature search (1983-1993) did not reveal prior reports of stroke linked to the nasal use of these specific agents.

    • Implications:

    • This case suggests a potential, previously undocumented risk of ischemic stroke associated with the nasal use of amphetamine and caffeine.
    • Transient arterial hypertension induced by these substances may be a critical mediator.
    • Highlights the importance of considering substance abuse in the differential diagnosis of stroke, even in younger individuals.