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Inbreeding and developmental stability in a small human population

T A Markow1, J F Martin

  • 1Department of Zoology, Arizona State University.

Annals of Human Biology
|July 1, 1993
PubMed
Summary

Inbreeding in the Havasupai tribe is linked to reduced developmental stability. Analysis of dermatoglyphic traits indicates that inbreeding compromises developmental homeostasis in this isolated population.

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Area of Science:

  • Human genetics
  • Developmental biology
  • Anthropology

Background:

  • Inbreeding is known to reduce developmental homeostasis across many species.
  • The Havasupai tribe in Arizona presents a unique, isolated population for genetic study.

Purpose of the Study:

  • To investigate the association between inbreeding levels and developmental stability in the Havasupai tribe.
  • To determine if inbreeding impacts developmental homeostasis in this human population.

Main Methods:

  • Calculated inbreeding coefficients for Havasupai individuals using up to eight generations of pedigree data.
  • Assessed developmental stability by measuring fluctuating asymmetry in two dermatoglyphic traits.

Main Results:

  • Inbreeding coefficients were determined for all Havasupai tribe members.
  • A significant association was found between higher inbreeding and increased fluctuating asymmetry.
  • This suggests compromised developmental homeostasis in more inbred individuals.

Conclusions:

  • Inbreeding significantly compromises developmental homeostasis in the Havasupai population.
  • Fluctuating asymmetry in dermatoglyphic traits serves as a reliable indicator of inbreeding effects on developmental stability.

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