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Related Experiment Videos

Thromboembolism in patients undergoing thoracotomy

S Ziomek1, R C Read, H G Tobler

  • 1McClellan Memorial Veterans' Hospital, Little Rock, AR 72205.

The Annals of Thoracic Surgery
|August 1, 1993
PubMed
Summary

This study found that 26% of patients undergoing thoracotomy experienced thromboembolic events. Prophylaxis with aspirin or ibuprofen showed promise in preventing postoperative deep venous thrombosis and pulmonary embolism.

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Area of Science:

  • Cardiovascular Medicine
  • Thoracic Surgery
  • Oncology

Background:

  • Thoracotomy is a major surgical procedure with potential risks.
  • Thromboembolic events, including deep venous thrombosis and pulmonary embolism, are significant complications.
  • Understanding the incidence and risk factors for these events is crucial for patient management.

Purpose of the Study:

  • To determine the incidence of thromboembolic events following thoracotomy.
  • To identify risk factors associated with postoperative thromboembolism.
  • To evaluate the potential benefit of preoperative aspirin or ibuprofen in preventing these events.

Main Methods:

  • Prospective study of 77 patients undergoing pulmonary resection.
  • Monitoring for deep venous thrombosis and pulmonary embolism up to 30 days postoperatively.

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  • Analysis of patient data including cancer type, tumor size, stage, and surgical procedure.

    • Main Results:

    • Overall thromboembolic event incidence was 26% (20/77).
    • Postoperative incidence was 19% (15/77), with deep venous thrombosis in 14% and pulmonary embolism in 5%.
    • No thromboembolic events occurred in patients receiving preoperative aspirin or ibuprofen (n=17), compared to 25% in others (15/60).

    Conclusions:

    • Thromboembolism after pulmonary resection is more frequent in patients with bronchogenic carcinoma, adenocarcinoma, larger tumors, advanced stage, and major resections (pneumonectomy/lobectomy).
    • Preoperative aspirin or ibuprofen may reduce postoperative thromboembolic events.
    • Patients undergoing thoracotomy for lung cancer, particularly adenocarcinoma, should be considered for thromboembolic prophylaxis.