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Related Experiment Videos

Defining normal ambulatory blood pressure

E O'Brien1, N Atkins, K O'Malley

  • 1Blood Pressure Unit, Beaumont Hospital, Dublin, Ireland.

American Journal of Hypertension
|June 1, 1993
PubMed
Summary
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Establishing normal blood pressure (BP) reference values is crucial. Ambulatory blood pressure (ABP) monitoring offers the best correlation with end-organ damage, guiding clinical practice.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Measurement

Background:

  • Defining normal reference values for blood pressure (BP) measurement is an urgent clinical need.
  • Ambulatory blood pressure (ABP) monitoring is increasingly recognized for its diagnostic value.
  • Current methods for establishing BP normalcy lack universal consensus.

Purpose of the Study:

  • To review and evaluate different approaches for defining normal ambulatory blood pressure (ABP) values.
  • To identify the most scientifically robust methods for establishing BP reference ranges.
  • To provide practical, rounded upper limits for 24-hour, daytime, and nighttime ABP.

Main Methods:

  • Consideration of five distinct approaches to defining BP normalcy.
  • Analysis of the relationship between ABP and morbidity/mortality.

Related Experiment Videos

  • Evaluation of ABP correlation with end-organ damage.
  • Assessment of ABP in normal population samples.
  • Comparison of ABP with clinic BP measurements.

    • Main Results:

    • The relationship of ABP to morbidity/mortality and end-organ involvement are the most scientifically sound approaches.
    • Ambulatory BP measurement shows a stronger correlation with end-organ damage than traditional methods.
    • Calculated rounded upper limits for normal ABP are 140/90 mm Hg (24-hour), 150/90 mm Hg (daytime), and 130/80 mm Hg (nighttime).

    Conclusions:

    • While definitive normalcy levels require further derivation, current data allows for practical clinical guidelines.
    • ABP monitoring is superior for assessing cardiovascular risk and end-organ damage.
    • Age and gender-specific differences in ABP must be considered for accurate interpretation.