Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

"Keyhole" method for accelerating imaging of contrast agent uptake

J J van Vaals1, M E Brummer, W T Dixon

  • 1Philips Medical Systems, Best, The Netherlands.

Journal of Magnetic Resonance Imaging : JMRI
|July 1, 1993
PubMed
Summary

Accelerated magnetic resonance (MR) imaging uses reference data instead of missing data to reduce blurring. This technique significantly speeds up imaging for better contrast agent tracking in patients and volunteers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ovariectomy-induced depressive-like behavior and brain glucose metabolism changes in female rats are not affected by chronic mild stress.

Psychoneuroendocrinology·2020
Same author

Serotonergic compounds in panic disorder, obsessive-compulsive disorder and anxious depression: A concise review.

Human psychopharmacology·2018
Same author

Heterozygosity for ARID2 loss-of-function mutations in individuals with a Coffin-Siris syndrome-like phenotype.

Human genetics·2017
Same author

Identification of new TRIP12 variants and detailed clinical evaluation of individuals with non-syndromic intellectual disability with or without autism.

Human genetics·2016
Same author

Comprehensive review of the duplication 3q syndrome and report of a patient with Currarino syndrome and de novo duplication 3q26.32-q27.2.

Clinical genetics·2016
Same author

Considering depression as a consequence of activation of the inflammatory response system.

Acta neuropsychiatrica·2016

Area of Science:

  • Medical Imaging
  • Radiology
  • Biomedical Engineering

Background:

  • Current magnetic resonance (MR) imaging methods lack the speed for optimal contrast agent uptake visualization.
  • High spatial and contrast resolution in MR imaging often compromises temporal resolution, limiting dynamic studies.

Purpose of the Study:

  • To develop and validate an accelerated MR imaging technique for improved contrast agent tracking.
  • To reduce blurring artifacts commonly seen in accelerated MR imaging by employing a novel data substitution method.

Main Methods:

  • Accelerated MR imaging by acquiring only weak-gradient data, omitting strong-gradient data acquisition.
  • Substitution of missing k-space data with pre- or post-contrast reference scans instead of zero-filling.
  • Application of the method to both gradient-echo and spin-echo sequences in volunteer and patient studies.

Related Experiment Videos

Main Results:

  • Significantly reduced blurring artifacts compared to traditional zero-filling methods in accelerated MR imaging.
  • Demonstrated severalfold acceleration of imaging acquisition while maintaining diagnostic image quality.
  • Successful visualization of cortical, medullary, and whole kidney regions with enhanced temporal resolution.

Conclusions:

  • The proposed reference data substitution method effectively accelerates MR imaging without significant image degradation.
  • This technique offers a viable solution for dynamic contrast-enhanced MR imaging, improving temporal resolution.
  • The method is compatible with other acceleration strategies, potentially enabling further speed enhancements.