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Updated: May 5, 2026

Measuring Peptide Translocation into Large Unilamellar Vesicles
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Measuring Peptide Translocation into Large Unilamellar Vesicles

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TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

J C Shepherd1, T N Schumacher, P G Ashton-Rickardt

  • 1Division of Immunobiology FMB402, Howard Hughes Medical Institute, Yale Medical School, New Haven, Connecticut 06510.

Cell
|August 13, 1993
PubMed
Summary

Transporters associated with antigen processing (TAP) 1 and 2 are crucial for T cell recognition of infected cells. This study shows TAP1 functions as an ATP-dependent peptide translocator in a cell-free system.

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