[Personal experience with immunosuppressive therapy of endogenous uveitis]

The authors investigated 43 patients with the original diagnosis of endogenous idiopathic uveitis for a period of one year. Comprehensive ophthalmological, immunological and rheumatological examination revealed that in all investigated cases either systemic disease was involved or diseases associated with impaired immunity or endogenous idiopathic uveitis. The patients were treated by immunosuppressive therapy either by Prednisone alone or by a combination of Prednisone and Cyclophosphamide. In all instances remission was achieved, contrary to previous therapy employed in these patients. In the majority of patients/21 of 23 and 12 of 18 resp./remission persisted for at least one year. The authors discuss indications and pitfalls of immunosuppressive therapy based on recommendations found in the literature.