Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retroperitoneal fibrosis and inapparent obstructive uropathy

A F Lalli

    Radiology
    |February 1, 1977
    PubMed
    Summary

    Retroperitoneal fibrosis can cause severe renal failure with minimal caliectasis, suggesting this diagnosis for unexplained kidney issues. This condition may affect ureteral function rather than causing direct obstruction.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Opinion: contrast media, ionic and non-ionic, a personal view.

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes·1988
    Same author

    Contrast media deaths.

    Australasian radiology·1984
    Same author

    Iohexol in urography.

    Urologic radiology·1983
    Same author

    Renal Parenchyma calcifications.

    Seminars in roentgenology·1982
    Same author

    Hypotension following contrast media injection during general anesthesia.

    Anesthesia and analgesia·1982
    Same author

    Potential applications of digital angiography in GU imaging.

    Urologic radiology·1982

    Area of Science:

    • Nephrology
    • Urology
    • Pathology

    Background:

    • Retroperitoneal fibrosis is a condition that can lead to severe renal failure.
    • The degree of caliectasis (dilation of the renal pelvis) in these patients is often disproportionately minor.
    • This finding can be a key diagnostic clue for retroperitoneal fibrosis.

    Purpose of the Study:

    • To highlight the diagnostic significance of minor caliectasis in severe renal failure associated with retroperitoneal fibrosis.
    • To explore the potential mechanisms behind this observation, focusing on ureteral dynamics.

    Main Methods:

    • Retrospective analysis of 21 patients diagnosed with retroperitoneal fibrosis.
    • Clinical data review, including renal function, imaging findings, and patient history.
    • Assessment of ureteral function and potential causes of renal failure.

    Main Results:

    • Patients with retroperitoneal fibrosis and severe renal failure often showed only mild caliectasis.
    • A potential mechanism involves interference with ureteral peristalsis rather than mechanical obstruction.
    • The typical patient demographic was male, aged 40-55 years.
    • Associated conditions included cardiac disease (2 patients) and prolonged methysergide use (31 patients).

    Conclusions:

    • Minor caliectasis in the context of severe renal failure should raise suspicion for retroperitoneal fibrosis.
    • Ureteral dynamic dysfunction appears to be a more likely cause of renal impairment than direct ureteral obstruction.
    • Treatment led to improvement or cure in 18 patients, with 3 deaths.

    Related Experiment Videos