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Inflammatory ulcers

F A Kerdel1

  • 1Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Florida.

The Journal of Dermatologic Surgery and Oncology
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

Inflammatory disorders can cause skin ulcers. This review focuses on vasculitis, small vessel thrombi/emboli, and pyoderma gangrenosum, highlighting recent advancements in understanding and treatment.

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Area of Science:

  • Dermatology
  • Internal Medicine
  • Pathology

Background:

  • Cutaneous ulceration is a common manifestation of numerous diseases.
  • Inflammatory conditions are a significant cause of skin breakdown and ulcer formation.
  • Recent advancements necessitate updated reviews of specific inflammatory dermatoses.

Purpose of the Study:

  • To review inflammatory disorders that directly cause cutaneous ulceration.
  • To emphasize conditions with recent advances in understanding or therapeutics.
  • To focus on vasculitis, small vessel thrombi/emboli, and pyoderma gangrenosum.

Main Methods:

  • Literature review of inflammatory dermatoses leading to ulceration.
  • Focus on conditions with new therapeutic agents or improved understanding.

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  • Synthesis of current knowledge on specific vasculitides and pyoderma gangrenosum.

    • Main Results:

    • Vasculitis, small vessel thrombi/emboli, and pyoderma gangrenosum are key inflammatory causes of skin ulcers.
    • New therapeutic strategies and enhancedpathophysiological insights are available for these conditions.
    • Understanding the specific mechanisms is crucial for effective management.

    Conclusions:

    • Inflammatory disorders remain a critical area for the etiology of cutaneous ulcers.
    • Advances in understanding and treatment offer improved patient outcomes for vasculitis, thrombi/emboli disorders, and pyoderma gangrenosum.
    • Continued research into inflammatory skin ulceration is warranted.