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Interrelationship among prognostic factors in carcinoma breast
A Bhattacharya1, P Sur, S K Mallik
1BS Medical College Hospital, Bankura.
Journal of the Indian Medical Association
|March 1, 1993
Summary
Advanced breast cancer is common in rural West Bengal, with most patients presenting late. Delayed diagnosis of breast cancer leads to larger tumors and more lymph node involvement, indicating a poor prognosis.
Area of Science:
- Oncology
- Public Health
- Pathology
Background:
- Breast cancer presentation in rural West Bengal is frequently at an advanced stage.
- A significant delay in seeking medical attention is observed, with most cases presenting after 12 months of symptom onset.
Purpose of the Study:
- To analyze the clinical and pathological characteristics of advanced breast cancer cases in rural West Bengal.
- To highlight the implications of delayed diagnosis on disease severity and treatment outcomes.
Main Methods:
- Retrospective analysis of 32 breast cancer cases from rural West Bengal.
- Evaluation of tumor size, axillary lymph node status, and histological features including lymphovascular invasion.
Main Results:
- 65.6% of cases presented with a breast lump duration exceeding 12 months.
- 84.4% had large tumors (>5 cm) and 4+ positive axillary nodes; 87.5% had nodes ≥2 cm.
- High rates of lymph vessel invasion (96.9%) and blood vessel invasion (90.6%) were observed.
Conclusions:
- Late-stage presentation of breast cancer is prevalent in rural West Bengal, characterized by large tumors and extensive lymph node metastasis.
- The high incidence of lymphovascular invasion in these advanced cases suggests aggressive tumor biology and underscores the need for early detection strategies.