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Pure progressive aphemia

L Cohen1, N Benoit, P Van Eeckhout

  • 1Service de Neurologie, Hôpital de la Salpêtrière, Paris, France.

Journal of Neurology, Neurosurgery, and Psychiatry
|August 1, 1993
PubMed
Summary
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Aphemia, a rare speech disorder, typically stems from brain lesions. This case highlights aphemia as the only symptom of primary progressive aphasia (PPA).

Area of Science:

  • Neurology
  • Speech-Language Pathology
  • Neuroscience

Background:

  • Aphemia, also known as anarthria or severe apraxia of speech, is a rare motor speech disorder.
  • It typically results from vascular lesions impacting the left hemisphere's inferior premotor cortex.

Observation:

  • This report details a patient where aphemia was the sole clinical manifestation.
  • The patient's condition was identified as primary progressive aphasia (PPA).

Findings:

  • The study presents a unique case of aphemia as the singular symptom of PPA.
  • This challenges typical presentations of PPA, which often involve broader language deficits.

Implications:

  • This case expands the understanding of PPA's diverse clinical spectrum.

Related Experiment Videos

  • It underscores the importance of considering aphemia in the differential diagnosis of progressive language disorders.
  • Further research is warranted to explore the neurobiological underpinnings of isolated aphemia in PPA.