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Updated: Aug 14, 2026

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
Photosensitization with methylene-linked porphyrin dimers
D Kessel1, C K Chang, B W Henderson
1Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201.
Abstract:
The photodynamic therapy (PDT) efficacy of a series of porphyrin dimers linked by methylene groups was evaluated using the radiation-induced fibrosarcoma (RIF) tumor model. Longer chain length led to greater efficacy and increased dimer hydrophobicity. This result was correlated with the persistence of porphyrins in plasma, but not with tissue levels.
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