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Related Experiment Videos

[Sedation versus general anesthesia in pediatric endoscopy]

R Behrens1, A Seiler, T Rupprecht

  • 1Klinik und Poliklinik für Kinder und Jugendliche, Friedrich-Alexander-Universität Erlangen-Nürnberg.

Klinische Padiatrie
|May 1, 1993
PubMed
Summary

Intravenous sedation with midazolam and etomidat offers a comfortable and efficient alternative to general anesthesia for upper endoscopy. This method is recommended for most therapeutic endoscopy procedures, excluding esophageal varices sclerotherapy.

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Area of Science:

  • Gastroenterology
  • Anesthesiology
  • Medical Procedures

Background:

  • Upper endoscopy is a common diagnostic and therapeutic procedure.
  • Anesthesia choices impact patient comfort, procedure efficiency, and costs.
  • General anesthesia and sedation are primary options, each with distinct implications.

Purpose of the Study:

  • To compare the efficacy and patient experience of different sedation methods for upper endoscopy.
  • To evaluate general anesthesia, intravenous sedation with midazolam and etomidat, and no premedication.
  • To determine the optimal sedation strategy for routine and therapeutic endoscopy.

Main Methods:

  • A study involving 567 patients undergoing upper endoscopy.
  • Patients were divided into three groups: general anesthesia (237), intravenous sedation with midazolam and etomidat (261), and no premedication (69).

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  • Data on patient comfort, procedure duration, and resource utilization were assessed.

    • Main Results:

    • Procedures without premedication were frequently interrupted due to patient defense.
    • General anesthesia required more time, personnel, and incurred higher costs.
    • Intravenous sedation with midazolam and etomidat (0.26 mg/kg) provided the most comfort for patients and endoscopists, with shorter procedure times compared to general anesthesia.

    Conclusions:

    • Intravenous sedation with midazolam and etomidat is a highly recommended method for upper endoscopy.
    • This sedation technique enhances patient and endoscopist comfort and improves procedural efficiency.
    • It is advised for most therapeutic endoscopy applications, with the exception of esophageal varices sclerotherapy.