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Mixed phenotype murine leukemias
M P Defresne1, B Borremans, C Verhofstede
1Laboratory of Pathological Anatomy and Cytopathology, University of Liège, Sart Tilman, Belgium.
Leukemia
|August 1, 1993
Abstract:
Cell lines were derived from eight individual leukemias induced by X-rays in NFS mice. First typed as null cells (surface immunoglobulin negative, Thy-1 negative), they turned out to have a mixed phenotype with myeloid cytochemical markers, pre-B surface antigens and molecular markers of pro-B lymphocytes. They represent murine models for mixed phenotype (pro-pre-B-myeloid) leukemias.