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Updated: Aug 14, 2026

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
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Anti-Ri-associated paraneoplastic neurologic disorder without opsoclonus in a patient with breast cancer
D Escudero1, A Barnadas, M Codina
1Service of Neurology Hospital Clinic, Barcelona, Spain.
Abstract:
A 59-year-old woman with breast cancer and anti-Ri antibodies developed a neurologic paraneoplastic disorder characterized by nausea, vomiting, vertigo, paresis of upward gaze, and gait ataxia, without opsoclonus. The absence of opsoclonus does not rule out the possibility of an anti-Ri-associated paraneoplastic neurologic disorder.
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