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Updated: Aug 14, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
[Treatment of endometrial hyperplasia with Goserelin depot, an LH-RH analog]
M Pozzi1, D Castagnola, F Cherubini
1Divisione di Ginecologia Oncologica, Istituto Regina Elena per lo Studio e la Cura dei Tumori, Roma.
Abstract:
Nineteen patients with simple endometrial hyperplasia presenting metrorrhagia or menometrorrhagia were treated with 4 injections of Goserelin depot, one every 4 weeks. 12/19 patients were refractory after previous medical therapy. The treatment with Goserelin depot resulted in a complete remission of the symptoms, occurring within the first month of treatment and still present after a median follow-up of 12 months, and in the normalization of the histological profile. No patient experienced clinically relevant side effects.
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