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Torulopsis glabrata in the neonate: an emerging fungal pathogen
C Glick1, G R Graves, S Feldman
1Department of Pediatrics, University of Mississippi Medical Center, Jackson 39216-4505.
Abstract:
Fungi are becoming increasingly common nosocomial pathogens in the neonatal intensive care patient. The fungus Torulopsis glabrata, a common skin inhabitant, is a potential pathogen in the high-risk neonate. In this report we have reviewed the cases of two infants in which systemic T glabrata infection was diagnosed. One patient survived without apparent sequelae; the other died before diagnosis and initiation of therapy. Five other cases of systemic infection by T glabrata in neonates have been reported previously, with only one survivor. Early recognition and treatment of this nearly uniformly fatal infection is imperative.
Insights
Torulopsis glabrata is an emerging fungal pathogen in neonatal intensive care units. Early diagnosis and treatment are crucial for survival in neonates with this systemic infection.
Area of Science:
- Medical Mycology
- Neonatal Infectious Diseases
- Hospital-Acquired Infections
Background:
- Fungal infections are a growing concern in neonatal intensive care units (NICUs).
- Torulopsis glabrata (Candida glabrata), a common skin commensal, poses a significant risk to vulnerable neonates.
- Systemic T. glabrata infections are rare but carry a high mortality rate in this population.