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Updated: Aug 14, 2026

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
[Principles of radical treatment of soft tissue tumors (author's transl)]
Abstract:
Malignancy should always be suspected for any soft tissue tumor. Thus, histologic examination of the totally excised growth is mandatory. Amputation is indicated as a curative measure for recurrencies and lesions that cannot be excised locally. It is also indicated for palliation in cases with ulceration, impaired function, and distant metastases. Adjuvant radio- and chemotherapy, based on the type of tumor, is outlined. The importance of cooperation between surgeon, pathologist, radiologist, and chemotherapist and of a central soft tissue tumor register is emphasized.

