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Updated: Jul 10, 2026

Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
[Apple-peel jejunal atresia. Nutritional management]
T Lamireau1, M Janoyer, B Llanas
1Unité de Réanimation Infantile (Pr B. Sandler), Hôpital des Enfants, Bordeaux.
Apple-peel jejunal atresia, a rare congenital defect, was managed using a novel three-stage approach. This method involved drip-feeding a nutrient mixture to promote gut health in infants with short gut syndrome.
Area of Science:
- Digestive tract congenital defects
- Pediatric surgery
- Gastroenterology
Background:
- Apple-peel jejunal atresia is a rare congenital anomaly.
- It is frequently associated with short gut syndrome, posing significant management challenges.
Observation:
- Two cases of apple-peel jejunal atresia were successfully managed.
- A three-stage approach combining medical and surgical interventions was employed.
Findings:
- The treatment involved drip-feeding a mixture of protein hydrolysate and jejunal secretions.
- This was administered through the distal ileostomy to enhance the trophicity of the remaining distal gut.
Implications:
- This approach offers a potential strategy for improving outcomes in complex pediatric gastrointestinal malformations.
- Stimulating distal gut trophicity may be crucial for managing short gut syndrome secondary to atresia.
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