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Characterisation of the central nervous depressant activity of a commercially available valerian root extract
J Leuschner1, J Müller, M Rudmann
1LPT Laboratory of Pharmacology, Hamburg, Fed. Rep. of Germany.
Arzneimittel-Forschung
|June 1, 1993
Abstract:
The evaluation of a commercially available valerian root extract (Valdispert) revealed pronounced sedative properties in the mouse with respect to a reduction in motility and an increase in the thiopental sleeping-time. A direct comparison with diazepam and chlorpromazine revealed a moderate sedative activity for the tested extract. The extract showed only weak anticonvulsive properties.