Related Experiment Video
Updated: Aug 6, 2026

Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics
Published on: November 27, 2017
How does sodium lauryl sulfate alter the skin barrier function in man? A multiparametric approach
J L Lévêque1, J de Rigal, D Saint-Léger
1Laboratoires de Recherche de l'Oréal, Aulnay-sous-Bois, France.
Abstract:
The effects of topically applied sodium lauryl sulfate were studied in vivo, in man, through noninvasive methods and compared with those obtained in vitro, using human stratum corneum as a model. The results show that the very marked increase of transepidermal water loss obtained in vivo cannot be related to any removal of epidermal lipids. The most likely explanation of our findings lies in the hyperhydration of stratum corneum consecutive to the inflammation process and a possible disorganization of the lipid bilayers.
More Related Videos
Related Concept Videos
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Staphylococcal Skin Infections

