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Necrotizing enterocolitis (NEC)--mortality and long-term results

T Kurscheid1, A M Holschneider

  • 1Hospital for Sick Children of Cologne, Department of Pediatric Surgery, KKA, Germany.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|June 1, 1993
PubMed
Summary

Necrotizing enterocolitis (NEC) affects premature infants, with higher mortality in non-low birth-weight babies. Breast milk and improved survival rates were observed, but long-term issues like feeding intolerance persist.

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Area of Science:

  • Pediatric Surgery
  • Neonatology
  • Gastroenterology

Background:

  • Necrotizing enterocolitis (NEC) is a severe gastrointestinal condition in neonates.
  • The study examines NEC cases treated surgically between 1974-1988.

Purpose of the Study:

  • To analyze clinical presentation, management, and outcomes of NEC in infants.
  • To identify risk factors and long-term sequelae associated with NEC.

Main Methods:

  • Retrospective review of 73 NEC patients treated surgically.
  • Analysis of clinical data, radiological findings, surgical interventions, and follow-up outcomes.

Main Results:

  • 77% of patients were premature; higher mortality in non-low birth-weight infants.

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  • Common symptoms included abdominal distension and bloody stools; radiology revealed bowel edema and free air.
  • Survival rates improved from 64% to 79% during the study period.
  • Survivors experienced issues like diarrhea, underweight, and food intolerance.

    • Conclusions:

    • NEC management requires prompt diagnosis and surgical intervention.
    • Breast milk feeding may be associated with a less severe disease course.
    • Long-term follow-up is crucial for addressing persistent complications in NEC survivors.