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[Antibiotic therapy in the intensive care unit]
1I. interná klinika NsP akad. L. Dérera, výucbová základna IVZ, v Bratislave, Slovakia.
Bratislavske Lekarske Listy
|March 1, 1993
Summary
Antibiotic treatment was evaluated in 78 patients with serious infections. While overall prognosis was poor, specific antibiotics like ofloxacin, ciprofloxacin, doxycycline, and cotrimoxazole showed effectiveness for certain conditions, including in dialysis patients.
Area of Science:
- Infectious Diseases
- Pharmacology
Context:
- Reports on antibiotic treatment outcomes for 78 patients over one year.
- Highlights the challenge of nosocomial infections and severe patient conditions.
- Addresses patients with comorbidities, including those on dialysis and with chronic bronchitis.
Purpose:
- To evaluate the effectiveness of various antibiotic treatments in a cohort of hospitalized patients.
- To identify specific antibiotic efficacy based on infection type and patient characteristics.
- To assess the need for antibiotic therapy in patients with cardiac pacemakers.
Summary:
- Despite adequate antibiotic therapy, prognosis remained unfavorable due to nosocomial infections and severe patient conditions.
- Ofloxacin and ciprofloxacin were effective in dialysis patients.
- Doxycycline showed efficacy in chronic bronchitis exacerbations.
- Cotrimoxazole confirmed its effectiveness for urinary tract infections.
- Antibiotics were administered to 18 of 78 patients with cardiac pacemakers for prophylaxis or treatment of respiratory/urinary tract infections.
Impact:
- Demonstrates the challenges in treating severe nosocomial infections.
- Provides evidence for targeted antibiotic selection in specific patient subgroups (dialysis, chronic bronchitis).
- Indicates that a majority of cardiac pacemaker patients do not require antibacterial treatment post-implantation.