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Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
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[Changes in plasma and urinary digoxin-immunoreactive like substance in normal pregnancy and pregnancy-induced

A Q Li1, Z J Zhang

  • 1Obstetrics and Gynecological Hospital, Shanghai Medical University.

Zhonghua Fu Chan Ke Za Zhi
|March 1, 1993
PubMed

Plasma and urinary digoxin-immunoreactive like substance (DILS) were measured in normal non-pregnant (NNP), normal pregnant (NP) and pregnancy-induced hypertensive women (PIH). The plasma DILS level of PIH, compared with NNP, was no significantly decreased (P > 0.05); but that of NP was significantly decreased (P < 0.01). While the urinary DILS levels of PIH and NNP were significantly higher than that in NNP (P < 0.01). In 24-72 hours after delivery the plasma and urinary DILS levels were all significantly lower than that in NNP (P < 0.05). These results indicate that DILS may play a role in homeostasis regulation in NP or PIH.

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