Related Experiment Videos
[Fetal choroid plexus cysts: a real dilemma!]
F G Bratta1, F Romano, E Di Naro
1Istituto di Clinica Ostetrica e Ginecologica I, Facoltà di Medicina e Chirurgia, Università degli Studi di Bari.
Minerva Ginecologica
|June 1, 1993
Summary
Fetal choroid plexus cysts are observed in 1.07% of pregnancies. Even isolated cysts warrant detailed fetal morphology assessment and prenatal cytogenetic analysis due to potential chromosomal anomalies.
Area of Science:
- Prenatal diagnosis
- Fetal medicine
- Medical imaging
Background:
- Fetal choroid plexus cysts (CPCs) are common prenatal findings.
- Their clinical significance and association with chromosomal anomalies remain debated.
- Discordant opinions exist regarding the necessity of karyotype analysis for CPCs.
Purpose of the Study:
- To determine the incidence of fetal CPCs.
- To evaluate the association between CPCs and fetal anomalies.
- To establish optimal obstetrical management for fetuses with CPCs.
Main Methods:
- Prospective study of 834 routine ultrasonographic examinations at 18-21 weeks' gestational age.
- Evaluation of fetal morphology and presence of CPCs.
- Karyotype analysis performed in all cases with CPCs.
Main Results:
- Incidence of fetal CPCs was 1.07% (9 out of 834 fetuses).
- Three cysts were larger than 1 cm, and three were bilateral.
- One case of Trisomy 18 was diagnosed in a fetus with a large CPC and diaphragmatic hernia.
Conclusions:
- The presence of fetal CPCs necessitates a thorough ultrasonographic evaluation of fetal morphology.
- Despite spontaneous resolution, persistent or large cysts may indicate underlying issues.
- Prenatal cytogenetic analysis is recommended for all fetuses with CPCs to rule out chromosomal abnormalities.