Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chorioamnionitis and bacterial vaginosis

R S Gibbs1

  • 1Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center.

American Journal of Obstetrics and Gynecology
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The interrelationship of complement-activation fragments and angiogenesis-related factors in early pregnancy and their association with pre-eclampsia.

BJOG : an international journal of obstetrics and gynaecology·2010
Same author

A Randomized Controlled Trial of Metronidazole Vaginal Cream in the Treatment of Papanicolaou Smears Showing Atypical Squamous Cells of Undetermined Significance (ASCUS).

Journal of lower genital tract disease·2006
Same author

A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy.

Infectious diseases in obstetrics and gynecology·2002
Same author

The relationship between infections and adverse pregnancy outcomes: an overview.

Annals of periodontology·2002
Same author

Impact of infectious diseases on women's health: 1776-2026.

Obstetrics and gynecology·2001
Same author

Histologic inflammation in the maternal and fetal compartments in a rabbit model of acute intra-amniotic infection.

American journal of obstetrics and gynecology·2000

Bacterial vaginosis is linked to intraamniotic infection, with similar key bacteria found in both conditions. This association suggests BV may increase the risk of intraamniotic infection during pregnancy.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Microbiology

Background:

  • Bacterial vaginosis (BV) and intraamniotic infection (IAI) are distinct conditions.
  • Recent research indicates a potential link between BV and IAI.

Purpose of the Study:

  • To investigate the association between bacterial vaginosis and intraamniotic infection.
  • To identify common microorganisms in both conditions.

Main Methods:

  • Review of existing data on BV, IAI, and chorioamnionitis.
  • Analysis of microbial composition in clinical intraamniotic infection and bacterial vaginosis.
  • Epidemiologic studies in high-risk and lower-risk pregnant women.
  • Logistic regression analysis to assess relationships between microbial isolation and BV.

Related Experiment Videos

Main Results:

  • Microorganisms in BV and IAI are similar, with anaerobes, Gardnerella vaginalis, and Mycoplasma hominis predominant.
  • BV is associated with the development of IAI in both high-risk and antepartum women.
  • Histologic inflammation of placental membranes correlates with IAI and positive placental cultures.
  • A relationship exists between chorioamnion organism isolation and BV.

Conclusions:

  • Bacterial vaginosis is strongly associated with clinical intraamniotic infection and histologic chorioamnionitis.
  • The shared microbial profiles suggest a potential causal link or common pathway.
  • BV may be a significant risk factor for intraamniotic infection in pregnant women.