A burn patient resuscitation therapy designed by computer simulation (BET). Part 1: Simulation studies

Area of Science:

• Medical Simulation
• Burn Management
• Resuscitation Science

Background:

• Burn injuries cause significant fluid, electrolyte, and colloid imbalances during the shock phase.
• Previous resuscitation methods have limitations and potential side effects.
• Accurate assessment of patient needs is critical for effective burn shock management.

Purpose of the Study:

• To analyze fluid, electrolyte, and colloid requirements in burn patients during the shock phase.
• To design and evaluate a novel fluid therapy method (BET) for burn patients.
• To validate the effectiveness and safety of the BET method using a digital simulation.

Main Methods:

• Utilized a validated digital simulation technique for burn patient analysis.
• Analyzed the physiological repercussions of burns and various resuscitation protocols.
• Developed the Burn patient Effective Therapy (BET) method based on simulation data.

Main Results:

• The BET method demonstrated effectiveness in managing fluid and colloid needs.
• The BET method is characterized by a low infusion volume of resuscitation solution (220 ml/h/m2 BBSA).
• The BET method employs rapid and high-volume colloidal substance administration with specific concentration gradients.

Conclusions:

• The BET method offers an effective approach to fluid resuscitation in burn patients during shock.
• The BET method is associated with minimal side effects compared to traditional methods.
• Digital simulation is a valuable tool for designing and optimizing burn resuscitation strategies.